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宋福平

      

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宋福平,男。黑龙江省哈尔滨人。现任中国农业科学院植物保护研究所研究员,博士生导师。入选科技部“创新人才推进计划”中青年科技创新领军人才和国家高层次人才特殊支持计划。入选中国农科院“农科英才领军人才B类”

1991年获得复旦大学学士学位,1998年和2001年先后获得东北农业大学硕士和博士学位。2001至2003年在中国农业科学院生物技术研究所开展博士后研究工作。2007年12月至2008年12月在法国国家农业科学院(INRAE)开展博士后研究工作。2003年至今在中国农业科学院植物保护研究所工作。

长期从事杀虫微生物农药创制的应用基础研究。以苏云金芽胞杆菌(Bt)为材料,开展重要功能基因的发掘和转录调控机制、代谢途径调控机制和原核细胞的发育与分化机制等研究,以期发现遗传改良的新策略,从而创制新型、高效和长效微生物农药。先后主持了国家自然科学基金青年基金、面上项目、重点项目、863计划项目、973计划子课题、国家转基因产业化专项和国家重点研发计划等多项课题。建立了Bt杀虫基因的鉴定体系,分离克隆多种新型杀虫基因;揭示了重要杀虫基因的转录调控机制和杀虫蛋白合成的代谢调控机制;发现了母细胞裂解关键基因和决定芽胞和晶体细胞分化的重要转录因子。在国内外期刊上共发表了100余篇论文,其中SCI论文60余篇,以第一作者或通讯作者在ISME J、Gut Microbes、FASEB J、Microbiology Spectrum、Applied and Environmental Microbiology、 Applied Microbiology and Biotechnology和Molecular Microbiology等国际重要期刊上发表SCI论文30多篇,获得国家授权发明专利30多项。

联系方式:

Email: fpsong@ippcaas.cn

电话:13641211263,010-62896634


部分通讯作者论文:

1. Shuo Hou#, Ruibin Zhang#, Didier Lereclus, Qi Peng, Jie Zhang, Leyla Slamti, Fuping Song*. 2022. The transcription factor CpcR determines cell fate by modulating the initiation of sporulation in Bacillus thuringiensis .  Appl Environ Microbiol . 88(6):e0237421. doi: 10.1128/aem.02374-21. (IF="5.0)

2. Xinlu Liu#, Ruibin Zhang#, Shuo Hou, Huanhuan Liu, Jiaojiao Wang, Qingyue Yu, Qi Peng, Fuping Song*. 2021. Identification and Functional Characterization of Two Homologous SpoVS Proteins Involved in Sporulation of  Bacillus thuringiensis .  Microbiol Spectr. 9(2):e0088121 (IF="9.0)."  

3. Xinxin Shen#, Qingyue Yu#, Huanhuan Liu, Jiaojiao Wang, Ruibin Zhang, Qi Peng, Fuping Song*. 2021. Transition Phase Regulator AbrB Positively Regulates the  sip1Ab1 Gene Expression in  Bacillus thuringiensis .  Microbiol Spectr. 9(1):e0007521. (IF="9.0).

4. Qi Peng*, Xin Zhao, Jilong Wen, Minzhong Huang, Jie Zhang, Fuping Song*. 2020. Transcription in the acetoin catabolic pathway is regulated by AcoR and CcpA in  Bacillus thuringiensis .  Microbiological Research . 235(2020) 126438. (IF="5.0)"

5. Ruibin Zhang, Leyla Slamti , Lei Tong, Emilie Verplaetse, Lixia Ma, Christelle Lemy, Qi Peng, Shuyuan Guo, Jie Zhang, Fuping Song*, Didier Lereclus*. 2020. The stationary phase regulator CpcR activates  cry gene expression in non-sporulating cells of  Bacillus thuringiensis .  Molecular Microbiology . 113:740-754. (封面文章)(IF=3.9)

6. Qi Peng, Qingyue Yu, Fuping Song*. 2019. Expression of  cry genes in  Bacillus  thuringiensis biotechnology.  Applied Microbiology and Biotechnology. 103(4):1617-1626 (Review). (IF="5.6)

7. Jing Lv, Xin Zhang, Tantan Gao, Tingting Cui, Qi Peng, Jie Zhang, Fuping Song*.2019. Effect of the  spoIIID mutation on mother cell lysis in  Bacillus  thuringiensis . Applied Microbiology and Biotechnology. 103(10):4103-4112.

8. Xin Zhang, Tantan Gao, Qi Peng, Lai Song, Jie Zhang, Yunrong Chai, ,Dongmei Sun, Fuping Song*. 2018. A strong promoter of a non-cry gene directs expression of the  cry1Ac gene in  Bacillus thuringiensis .  Applied Microbiology and Biotechnology. 102(8):3687-3699. doi: 10.1007/s00253-018-8836-5.

9. Chen Xiaomin, Gao Tantan, Peng Qi, Zhang Jie, Chai Yunrong, Song Fuping*. 2018. Novel cell wall hydrolase CwlC from  Bacillus thuringiensis is essential for mother cell lysis.  Appl Environ Microbiol.  84:e02640-17. https://doi.org/10.1128/AEM.02640-17.

10. Zhiru Song#, Qi Peng#, Changlong Shu, Jie Zhang, Dongmei Sun*, Fuping Song*. 2017. Identification of similar transcriptional regulatory mechanisms in multiple  cry genes in  Bacillus thuringiensis HD12.  Journal of Integrative Agriculture . 16(1): 135-143. (IF="4.3)

11. Qi Peng, Jianbo Wu, Xiaomin Chen, Lili Qiu, Jie Zhang, Hongtoa Tian* and Fuping Song*. 2017. Disruption of Two-component System LytSR Affects Forespore Engulfment in  Bacillus thuringiensis .  Frontiers in Cellular and Infection Microbiology  7:468. (IF=6.0)

12. Qi Peng, Guiwei Kao, Ning Qu, , Jie Zhang, Jie Li, Fuping Song*. 2016. The regulation of exosporium-related genes in  Bacillus thuringiensis. Scientific Reports . 6: 19005, DOI: 10.1038/srep19005. (IF=5.0)

13. Deng Chao, Slamti L, Raymond Ben, Liu Guiming, Lemy C, Gominet M, Yang Jingni, Wang Hengliang, Peng Qi, Zhang Jie, Lereclus Didier*, Fuping Song*. 2015. Division of labour and terminal differentiation in a novel  Bacillus thuringiensis strain.  International Society for Microbial Ecology Journal, ISME J.  9: 286-296. (IF="11.2)

14. Qi Peng, Min Yang, Wei Wang, Lili Han, Guannan Wang, Pengyue Wang, Jie Zhang, Fuping Song*. 2014. Activation of  gab cluster transcription in  Bacillus thuringiensis byγ-aminobutyric acid or succinic semialdehyde is mediated by the Sigma 54-dependent transcriptional activator GabR.  BMC Microbiology . 14: 306-317. (IF="4.4)

15. Changmei Zhou, Qingyun Zheng, Qi Peng, Lixin Du, Changlong Shu, Jie Zhang, Fuping Song*. 2014. Screening of  cry -type promoters with strong activity and application in Cry protein encapsulation in a  sigK mutant.  Applied Microbiology and Biotechnology.  98: 7901-7909.

16. Zhe Zhang, Min Yang, Qi Peng, Guannan Wang, Qingyun Zheng, Jie Zhang, Fuping Song*. 2014. Transcription of the lysine-2, 3-aminomutase gene in the  kam locus of  Bacillus thuringiensis subsp.  kurstaki  HD73 Is controlled by both δ54 and δK factors.  Journal of Bacteriology.  196(16): 2934-2943. (IF="3.5)

17. Fuping Song, Qi Peng, Julien Brillard, Didier Lereclus, and Christina Nielsen-LeRoux*. 2014. An insect gut environment reveals the induction of a new sugar-phosphate sensor system in  Bacillus cereus .  Gut Microbes 5:1, 58–63. (IF5="12.1)

18. Chao Deng, Qi Peng, Fuping Song,* Didier Lereclus*. 2014. Regulation of cry gene expression in  Bacillus thuringiensis. Toxins . R6: 2194-2209. (Review) (IF="5.0)

19. Changlong Shu, Huiqin Su, Jie Zhang, Kanglai He, Dafang Huang, Fuping Song*. 2013. Characterization of  cry9Da4 ,  cry9Eb2 , and  cry9Ee1 genes from Bacillus thuringiensis strain T03B001.  Applied Microbiology and Biotechnology  .  97(22): 9705-9713.

20. Changlong Shu, Jingtao Zhang, Guihua Chen, Gemei Liang, Kanglai He, Neil Crickmore, Dafang Huang, Jie Zhang*, Fuping Song*. 2013. Use of a pooled clone method to isolate a novel  Bacillus thuringiensis Cry2A toxin with activity against  Ostrinia furnacalis .  Journal of Invertebrate Pathology . 114: 31-33. (IF="2.7)

21. Jingni Yang, Qi Peng, Zhen Chen, Chao Deng, Changlong Shu, Jie Zhang*, Dafang Huang, Fuping Song*. 2013. Transcriptional regulation and characteristics of a novel N- acetylmuramoyl - L-alanine amidase gene involved in  Bacillus thuringiensis  mother cell lysis.  Journal of Bacteriology. 195 (12): 2887-2897.

22. Lixin Du, Lili Qiu, Qi Peng, Didier Lereclus, Jie Zhang, Fuping Song*, Dafang Huang*. 2012. Identification of the promoter in the intergenic region between orf1 and  cry8Ea1 controlled by Sigma H factor.  Applied and Environmental Microbiology.  78: 4164-4168.

23. Hui Yang, Pinshu Wang, Qi Peng, Rong Rong, Chunxia Liu, Didier Lereclus, Jie Zhang, Fuping Song*, Dafang Huang*. 2012. Weak transcription of the  cry1Ac gene in nonsporulating  Bacillus thuringiensis cells.  Applied and Environmental Microbiology.  78: 6466-6474.

24. Fuping Song*, Qi Peng, Julien Brillard, Christophe Buisson, Mark de Been, Tjakko Abee, Véronique Broussolle, Dafang Huang, Jie Zhang, Didier Lereclus, Christina Nielsen - LeRoux*. 2012. A multicomponent sugar phosphate sensor system specifically induced in  Bacillus cereus during infection of the insect gut.  The FASEB Journal . 26: 3336-3353. (IF="5.8)

25. Li Zhu, Qi Peng, Fuping Song*, Yanan Jiang, Changpo Sun, Jie Zhang, Dafang Huang*. 2010. The structure and regulation of the  gab  gene cluster involved in the GABA shunt controlled by a σ54 factor in  Bacillus thuringiensis .  Journal of Bacteriology.  192(1): 346-355.