Professors
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Fax:
Email:hbzhou@ippcaas.cn
Web: https://www.researchgate.net/profile/Huanbin_Zhou/publications
Academic Title:Professor
Supervisor:Master Supervisor, PhD Supervisor
Department:Department of Biotechnology in Plant Protection
Group:Plant Genome Engineering
Education and Working Experience:
Education
B.S.1996-2000, Department of Horticulture, Huazhong Agricultural University, China
M.S. 2000-2003, College of Horticulture & Forestry, Huazhong Agricultural University, China
Ph.D. 2003-2007, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China
Work Experience
2007-2012, Department of Plant Pathology & Microbiology, University of California, Riverside, Postdoc
2012-2015, Department of Genetics, Development & Cell Biology, Iowa State University, Postdoc
2015-current, Plant Genome Engineering Group, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, China, Group leader
Research Area:
We mainly focus on exploring genes involved in rice-X. oryzae pv oryzae interactions with approaches of forward and reverse genetics, elite genes will be applied into molecular rice breeding via cutting-edge technology. Our current researches include:
1) dissecting the phytohormone signal network related to rice defense response against X. oryzae pv. oryzae.
2) constructing rice mutant population on a genome-wide scale by Cas9 nuclease.
3) unraveling the virulence functions of non-TAL effectors in X oryzae pv. oryzae.
4) developing a highly efficient CRIPSR/Knock-in system in rice.
Publications:
1. Zhou H, Liu B, Weeks DP, Spalding MH, Yang B. 2014. Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice. Nucleic Acids Research, 42(17):10903-10914
2. Jiang W, Zhou H, Bi H, Fromm M, Yang B, Weeks DP. 2013. Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice. Nucleic Acids Res. 41(20):e188.
3. Jiang S, Yao J, Ma KW, Zhou H, Song J, He SY, Ma W. 2013. Bacterial effector activates jasmonate signaling by directly targeting JAZ transcriptional repressors. PLoS Pathog. 9(10):e1003715.
4. Lewis JD, Lee A, Ma W, Zhou H, Guttman DS, Desveaux D. 2011. The YopJ superfamily in plant-associated bacteria. Mol Plant Pathol. 12(9):928-937
5. Wang GF, Wei X, Fan R, Zhou H, Wang X, Yu C, Dong L, Dong Z, Wang X, Kang Z, Ling H, Shen QH, Wang D, Zhang X. 2011. Molecular analysis of common wheat genes encoding three types of cytosolic heat shock protein 90 (Hsp90): functional involvement of cytosolic Hsp90s in the control of wheat seedling growth and disease resistance. New Phytol. 191(2):418-31
6. Zhou H, Lin J, Johnson A, Morgan RL, Zhong W, Ma W. 2011. Pseudomonas syringae type III effector HopZ1 targets a host enzyme to suppress isoflavone biosynthesis and promote infection in soybean. Cell Host & Microbe. 9(3):177-86
a) Commented by Andrew Bent. 2011. Pathogens Drop the Hint: Don't Forget Phytoalexin Pathways. Cell Host & Microbe. 9(3):169-70
7. Morgan RL, Zhou H, Lehto E, Nguyen N, Bains A, Wang X, Ma W. 2010. Catalytic domain of the diversified Pseudomonas syringae type III effector HopZ1 determines the allelic specificity in plant hosts. Mol Microbiol. 76(2):437-55
8. Zhou H, Morgan RL, Guttman DS, Ma W. 2009. Allelic variants of the Pseudomonas syringae type III effector HopZ1 are differentially recognized by plant resistance systems. Mol Plant Microbe Interact. 22(2):176-89
9. Zhou H, Li S, Deng Z, Wang X, Chen T, Zhang J, Chen S, Ling H, Zhang A, Wang D, Zhang X. 2007. Molecular analysis of three new receptor-like kinase genes from hexaploid wheat and evidence for their participation in the wheat hypersensitive response to stripe rust fungus infection. Plant J. 52(3):420-34