中文名：杨秋颖Education
B.S.1994--1998, Plant Molecular and Developmental Biology, College of Life Sciences, Peking University, China
Ph.D. 2001-2006, Plant Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China.
Work Experience
2007—2009, Cytoskeleton Laboratory, Institute of Botany, Chinese Academy of Sciences, China. Assistant Professor
2009—2015, Physiology Department, University of Texas, Southwestern Medical Center at Dallas, U.S.A. Postdoc Researcher
2009—2016, Microbiology Department, University of Texas, Southwestern Medical Center at Dallas, U.S.A. Research Associate
2016—current, Interaction of Plants and Viruses Laboratory, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, China. Professor
Research Area：
Small RNAs and small RNAs-mediated epigenetic modifications are key factors in Immune defense pathways against foreign nucleic acids, and key regulators in growth, development, differentiation, metabolism and reproduction pathways in Eukaryotes. Accompanying the viral infection and anti-viral defense of plants, small RNAs are generated from and against the viral genomes. In defending against viruses, innate immune responses are activated and RNA interference pathways are boosted in plants. However, viruses encode silencing suppressors to inhibit the RNA silencing pathways in order to change the cellular environment to suit viral life cycle, the consequence of which manifested as viral symptoms in plants.
Our study is to elucidate the mechanisms of small RNA biogenesis during viral infection, the influence of viral infection on the small RNA silencing pathways, plant morphology changes and viral symptoms development, the understanding of which will help in protecting the crops and contribute to the agricultural sciences.
Publications：
1. Qiuying Yang, Qiaohong Anne Ye and Yi Liu. Mechanism of Small Interfering RNA Production from Repetitive DNA (2015) Genes Dev. 29: 526-537.
2. Xiaoyong Sun*, Qiuying Yang*, Zhiping Deng, Xinfu Ye (2014) Digital inventory of Arabidopsis transcripts revealed by 61 RNA sequencing samples. Plant Physiol. Oct; 166(2):869-78. (*equal-contribution)
3. Zhenyu Zhang, Qiuying Yang, Guangyan Sun, She Chen, Qun He, Shaojie Li, Yi Liu (2014) Histone H3K56 acetylation is required for quelling-induced small RNA production through its role in homologous recombination. J Biol Chem. Mar 28; 289(13):9365-71.
4. Qiuying Yang, Liande Li, Zhihong Xue, Qiaohong Ye, Lin Zhang, Shaojie Li and Yi Liu (2013)Transcription of the major Neurospora microRNA-like small RNAs relies on RNA polymerase III. PLoS Genetics 2013 Jan; 9(1):e1003227
5. Meng Shi, Yurong Xie, Yiyan Zheng, Junmin Wang, Yi Su, Qiuying Yang, Shanjin Huang (2012) Oryza sativa actin-interacting protein 1 is required for rice growth via promoting actin turnover. The Plant Journal Mar;73(5):747-60
6. Yunkun Dang, Qiuying Yang, Zhihong Xue, and Yi Liu（2011）RNA interference in fungi: pathways, functions, and applications. Eukaryot Cell. 10(9):1148-55
7. Heng-Chi Lee, Antti P. Aalto, Qiuying Yang, Shwu-Shin Chang,Guocun Huang, Daniel Fisher, Joonseok Cha, Minna M. Poranen, Dennis H. Bamford, and Yi Liu (2010) The DNA/RNA-Dependent RNA Polymerase QDE-1 Generates aberrant RNA and dsRNA for RNAi in a process requiring replication protein A and a DNA helicase. PLoS Biol. v.8(10):
8. Yongbiao Xue*, Yijing Zhang*, Qiuying Yang *, Qun li, Zhukuan Cheng, Dickinson Hugh G. (2009) Genetic features of a pollen-part mutation suggest an inhibitory role for the Antirrhinum pollen self-incompatibility determinant. Plant Molecular Biology70(5):499-509 (*equal-contribution)
9. Qiuying Yang, Dongfen Zhang, Qun Li, Zhukuan Cheng, Yongbiao Xue (2007) Heterochromatic and genetic features are consistent with recombination suppression of the self-incompatibility locus in Antirrhinum. The Plant Journal 51(1):140-51.
10. Dongfen Zhang, Qiuying Yang, Yong Ding, Xiaofeng Cao, Yongbiao Xue, Zhukuan Cheng (2008) Cytological characterization of the tandem repetitive sequences and their methylation status in the Antirrhinum majus genome. Genomics 92: 107–114
11. Jian Huang, Lan Zhao, Qiuying Yang, Yongbiao Xue (2006) AhSSK1, a novel SKP1-like protein that interacts with the S-locus F-box protein SLF. The Plant Journal 46: 780–793
12. Weidong Bao, Wenli Zhang, Qiuying Yang, Yu Zhang, Bin Han, Minghong Gu, Yongbiao Xue, Zhukuan Cheng (2006) Diversity of centromeric repeats in two closely related wild rice species, Oryza officinalis and Oryza rhizomatis. Molecular Genetics and Genomics 275: 421–430
13. Dongfen Zhang*, Qiuying Yang *, Weidong Bao, Yu Zhang, Bin Han, Yongbiao Xue, Zhukuan Cheng (2005) Cytological characterization of the Antirrhinum majus genome.Genetics 169:325-335 (*equal-contribution)
