Effective and new multitarget pesticides, such as 20% abarmectin-monosultap microemulsion, 3% beta cypermethrin-emamectin microemulsion, 20% fenvalarate-malathion emulsifiable concentrates and 15% abamectin-chlorpyrifos emulsifiable concentrates, have been developed to control insect pests with resistance to multiple insecticides. The insecticides demonstrate high cotoxicity efficacy in laboratory and are effective on controlling pests such as H. armigera, Cnaphalocrocis medinalis, Liriomyza sativae, and Nilaparvata lugens in the field. Over two million tons of the insecticides have been deployed to control crop resistant pests.