Lang Liu, Zhongming Zhang, Chenyang Wang, Fang Yan, Wenxian Sun, Xueping Zhou, Weiguo Miao*, Huanbin Zhou*, Developing guanine base editors for G-to-T editing in rice.-中国农业科学院植物保护研究所

Lang Liu, Zhongming Zhang, Chenyang Wang, Fang Yan, Wenxian Sun, Xueping Zhou, Weiguo Miao, Huanbin Zhou, Developing guanine base editors for G-to-T editing in rice.

文章来源：J Integr Plant Biol 点击数：次发布时间：2025-03-11

J Integr Plant Biol, 2024, https:// doi: 10.1111/jipb.13729

Abstract

Two guanine base editors created using an engineered N-methylpurine DNA glycosylase with CRISPR systems achieved targeted G-to-T editing with 4.94-12.50% efficiency in rice (Oryza sativa). The combined use of the DNA glycosylase and deaminases enabled co-editing of target guanines with adenines or cytosines.

J Integr Plant Biol,IF=9.3

https://pubmed.ncbi.nlm.nih.gov/38934772/

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Lang Liu, Zhongming Zhang, Chenyang Wang, Fang Yan, Wenxian Sun, Xueping Zhou, Weiguo Miao*, Huanbin Zhou*, Developing guanine base editors for G-to-T editing in rice.

Lang Liu, Zhongming Zhang, Chenyang Wang, Fang Yan, Wenxian Sun, Xueping Zhou, Weiguo Miao, Huanbin Zhou, Developing guanine base editors for G-to-T editing in rice.