Annual Review of Entomology，2024，https://doi.org/10.1146/annurev-ento-013024-021018

 Abstract

(E)-β-farnesene (EBF) stands out as a crucial volatile organic compound,exerting significant influence on the complex interactions between plants,aphids, and predator insects. Serving as an alarm signal within aphids, EBFis also emitted by plants as a defense mechanism to attract aphid predators. This review delves into EBF sources, functions, biosynthesis, detectionmechanisms, and its coevolutionary impacts on aphids and insect predators. The exploration underscores the need to comprehend the biophysicaland structural foundations of EBF receptors in aphids, emphasizing theirrole in unraveling the intricate patterns and mechanisms of interaction between EBF and target receptors. Furthermore, we advocate for adoptingstructure-based or machine-learning methodologies to anticipate receptor–ligand interactions. On the basis of this knowledge, we propose futureresearch directions aiming at designing, optimizing, and screening morestable and efficient active odorants. A pivotal outcome of this comprehensive investigation aimsto contribute to the development of more effective aphid-targeted control strategies. 

Annual Review of Entomology，IF=15

https://www.annualreviews.org/content/journals/10.1146/annurev-ento-013024-021018