Despite extensive understanding of antiviral RNAi in plants, whether and how natural variation in components of RNAi contributes to antiviral immunity remains obscure.  Liu et al . recently identified novel positive and negative antiviral RNAi regulators, supporting RNAi's principal role in the dynamic virus–host coevolution in natural ecosystems.

Trends in Microbiology,  IF: 18.230

Doi: doi.org/10.1016/j.tim.2022.07.009