一、个人简介

张昊，男，博士， 2011年在中国农业科学院研究生院获得博士学位，同年进入到中国农科院植保所作物真菌病害流行与防控创新团队从事研究工作。主要研究方向为小麦病害综合防控，包括小麦赤霉病菌、茎基腐病菌群体遗传与演替机制、耕作制度对群体流行规律影响、产毒真菌与毒素快速检测、杀菌剂抗性检测等。通过大范围群体分析，明确了全国范围内赤霉菌与茎基腐菌的种群组成与分布，揭示了中国禾谷镰孢菌在不同轮作制度下的完整侵染循环，发现中国历史上人类大规模迁徙导致农业耕作制度改变，从而显著影响了小麦赤霉菌群体进化和生态适应性。在国际上首次发现半活体营养型真菌可以进行超过250公里的远距离传播，提出小麦赤霉病流行学的新见解。研发了小麦赤霉病智能化预报器，在全国10余个省份推广应用。

二、学术兼职

World Mycotoxin Journal 编委

Tropical Plant Pathology 编委

三、近年来主持和承担的课题

1. 国家重点研发计划课题：小麦赤霉病灾变规律与预测预报技术（2022YFD1400101）主持 2022.10-2026.10

2. 国家自然科学基金项目（面上）：基于群体基因组学的小麦赤霉病初侵染菌群遗传结构与适应性进化研究 (32172379) 主持 2022.1-2025.12

3. 新疆维吾尔自治区重点研发计划课题：伊犁河谷主要粮食作物病虫害绿色防控关键技术研发（2022B02015-3）主持 2022.12-2016.12

4. 国家重点研发计划-政府间国际科技创新合作重点专项：小麦赤霉病关键控制技术集成与创新 (2017YFE0126700) 主持 2019.8-2022.7

5.  国家自然科学基金项目（青年）：PEX基因在小麦赤霉菌生长发育与致病过程中的作用机制研究 (31201477) 主持 2013.1-2015.12

6. 国家重点研发计划-政府间国际科技创新合作重点专项：食品和饲料产业链中真菌毒素控制关键技术的集成与创新 (2016YFE0112900) 参加 2016.12-2019.12

7. 公益性行业（农业）科研专项经费项目：禾谷类白粉病和赤霉病综合治理技术研究与示范  (201303016 ) 参加 2013.1-2017.12

8.  国家国际合作专项项目：镰刀菌及其毒素的快速检测与控制技术研究 (2013DFG31930) 参加 2013.4-2016.3

四、主要研究方向

1. 镰孢菌群体遗传学

2. 镰孢菌及毒素快速检测与监测

3. 镰孢菌功能基因组学

五、主要论文（*通讯作者）

1. Yang MX, Smit S, de Ridder D, Feng J, Liu TG, Xu JR, van der Lee T*, Zhang H*, Chen WQ*. Adaptation of Fusarium head blight pathogens to changes in agricultural practices and human migration. Advanced Science. 2024, 11(36): 2401899.

2. Yang MX, Yi LS, Li GK, Liu TG, Zhang H*, Gao HF*. First report of crown rot caused by Fusarium graminearum on wheat in Xinjiang Uygur Autonomous Region, China. Plant Disease. 2024, 108(4): 1104.

3. Zhou LZ, Liu YQ, Kong FF, Jia SS, Wang Q, Wang ZY, Zhang H* and Huang XQ*. Sensitivity of Botrytis cinerea from vineyards to boscalid, isofetamid, and pydiflumetofen in Shandong Province, China. Phytopathology. 2024, 114:1068-1074.

4. Yi LS, Yang MX, Waalwijk C, Xu J, Xu JS, Molnár O, Chen WQ, Feng J, Zhang H*. Dynamics of carbendazim-resistance frequency of pathogens associated with the epidemic of Fusarium head blight. Plant Disease. 2023, 107(6): 1690-1696.

5. Huang XQ, Wang XN, Zhou LZ, Kong FF, Liu YQ, Wang ZY*, Zhang H*. TaqMan-MGB PCR method for rapid detection of QoI fungicide resistance in Chinese populations of Plasmopara viticola. Plant Disease. 2023, 107(10):3007-3013.

6. Yan Z, Chen WQ*, van der Lee T, Waalwijk C, van Diepeningen A, Feng J, Zhang H*, Liu TG*. Evaluation of Fusarium head blight resistance in 410 chinese wheat cultivars selected for their climate conditions and ecological niche using natural infection across three distinct experimental sites. Frontiers in Plant Science. 2022, 13: 916282.

7. Fan XF, Yan Z, Yang MX, Waalwijk C, van der Lee TAJ, van Diepeningen AD, Brankovics B, Chen WQ, Feng J*, Zhang H*. Contamination and translocation of deoxynivalenol and its derivatives associated with Fusarium crown rot of wheat in Northern China. Plant Disease. 2021, 105(11): 3397-3406.

8. Huang XQ, Wang XN, Kong FF, van der Lee TAJ, Wang ZY*, Zhang H*. Detection and characterization of carboxylic acid amide-resistant Plasmopara viticola in China using a TaqMan-MGB PCR. Plant Disease. 2020, 104(9): 2338-2345.

9. Yang MX#, Zhang H#, van der Lee TAJ, Waalwijk C, van Diepeningen AD, Feng J, Brankovics B, Chen WQ. Population genomic analysis reveals a highly conserved mitochondrial genome in Fusarium asiaticum. Frontiers in microbiology 2020, 11: 839.

10. Huang XQ, Xiao ZF, Kong F, Chen AJ, Perrone G, Wang ZY, Wang JL*, Zhang H*. Diversity and ochratoxin A-fumonisin profile of black Aspergilli isolated from grapes in China. World Mycotoxin Journal. 2020, 13(2): 225-233.

11. Yan Z#, Zhang H#, van der Lee TAJ, Waalwijk C, van Diepeningen AD, Deng Y, Feng J, Liu TG, Chen WQ. Resistance to Fusarium head blight and mycotoxin accumulation among 129 wheat cultivars from different ecological regions in China. World Mycotoxin Journal. 2020, 13(2): 189-199.

12. Kong XJ#, Zhang H#, Wang XL, van der Lee TAJ, Waalwijk C, van Diepeningen AD, Brankovics B, Xu J, Xu JS, Chen WQ, Feng J, FgPex3, a peroxisome biogenesis factor, is involved in regulating vegetative growth, conidiation, sexual development, and virulence in Fusarium graminearum. Frontiers in microbiology 2019, 10: 2088.

13. Yang MX#, Zhang H#, Kong XJ, van der Lee TAJ, Waalwijk C, van Diepeningen AD, Xu J, Xu JS, Chen WQ, Feng J. Host and cropping system shape the Fusarium population: 3ADON-producers are ubiquitous in wheat whereas NIV-producers are more prevalent in rice. Toxins. 2018, 10: 115.

14. Kong XJ, van Diepeningen AD, van der Lee TAJ, Waalwijk C, Xu JS, Xu J, Zhang H*, Chen WQ*, Feng J*. The Fusarium graminearum histone acetyltransferases are important for morphogenesis, DON biosynthesis, and pathogenicity. Frontiers in Microbiology. 2018, 9: 654.

15. Zhang H, Kong FF, Wang XN, Liang LS, Schoen CD, Wang ZY. Tetra-Primer ARMS PCR for rapid detection and characterization of Plasmopara viticola phenotypes resistant to carboxylic acid amide (CAA) fungicides. Pest Management Science. 2017, 73 (5): 557-563.

16. Waalwijk C, Vanheule A, Audenaert K, Zhang H, Warris S, van de Geest H, van der Lee T. Fusarium in the age of genomics. Tropical plant pathology. 2017, 42:1 84–189.

17. Kong XJ, Qin WT, Huang XQ, Kong FF, Schoen CD, Feng J, Wang ZY* and Zhang H*. Development and application of loop-mediated isothermal amplification (LAMP) for detection of Plasmopara viticola. Scientific Report. 2016, 6: 28935.

18. Zhang H, Brankovics B, van der Lee TAJ, Waalwijk C, van Diepeningen AD, Xu J, Xu JS, Chen WQ* and Feng J*. A single-nucleotide-polymorphism-based genotyping assay for simultaneous detection of different carbendazim-resistant genotypes in the Fusarium graminearum species complex. PeerJ. 2016, 4: e2609.

19. Zhang H, Brankovics B, Luo W, Xu J, Xu JS, Guo C, Guo JG, Jin SL, Chen WQ*, Feng J*, van Diepeningen AD, van der Lee TAJ and Waalwijk C. Crops are a main driver for species diversity and the toxigenic potential of Fusarium isolates in maize ears in China. World Mycotoxin Journal. 2016, 9 (5): 701-715.

20. Brankovics B, Zhang H, van Diepeningen AD, van der Lee TAJ, Waalwijk C, de Hoog GS. GRAbB: Selective Assembly of Genomic Regions, a New Niche for Genomic Research. PLoS Computational Biology. 2016. 12(6): e1004753.

21. van der Lee T, Zhang H, van Diepeningen A and Waalwijk C, Biogeography of Fusarium graminearum species complex and chemotypes: a review. Food Additives & Contaminants: Part A. 2015. 32(4): 453-463.

22. Zhang H, Luo W, Pan Y, Xu J, Xu JS, Chen WQ, and Feng J. First report of Fusarium ear rot of maize caused by Fusarium andiyazi in China. Plant Disease. 2014, 98(10): 1428.

23. Zhang H, Luo W, Pan Y, Xu J, Xu JS, Chen WQ, and Feng J. First report of Fusarium temperatum causing Fusarium ear rot on maize in Northern China. Plant Disease. 2014, 98(9): 1273.

24. Zhang H, Luo W, Pan Y, Xu J, Xu JS, Chen WQ, and Feng J. First report of Fusarium maize ear rot caused by Fusarium meridionale in China. Plant Disease. 2014, 98(8): 1156.

25. Zhang H, van der Lee TAJ, Waalwijk C, Chen WQ, Xu J, Xu JS, Zhang Y and Feng J*. Population analysis of the Fusarium graminearum species complex from wheat in China show a shift to more aggressive isolates. PLoS One. 2012, 7: e31722.

26. Zhang H, Chen W Q, Xu J, Xu J S, and Feng J*. First report of Fusarium cerealis causing Fusarium head blight on barely in China. Plant Disease. 2011, 95 (6): 774-775.

27. Zhang H, Zhang Z, van der Lee T, Chen W Q, Xu J, Xu J S, Yang L, Yu D, Waalwijk C, and Feng J*. Population genetic analyses of Fusarium asiaticum populations from barley suggest a recent shift favoring 3ADON producers in southern China. Phytopathology. 2010, 100 (4): 328-336.

28. Zhang Z#, Zhang H#, van der Lee T, Chen W Q, Arens P, Xu J, Xu J S, Yang L J, Yu D Z, Waalwijk C, and Feng J*. Geographic substructure of Fusarium asiaticum isolates collected from barley in China. European Journal of Plant Pathology. 2010, 127: 239-248.