周焕斌，男，中国农业科学院研究员、博士生导师。
2000年和2003年在华中农业大学园艺林学学院分别获蔬菜学学士和硕士学位，2007年在中国科学院遗传与发育生物学研究所获遗传学博士学位。2007至2015年分别在美国加州大学河滨分校、爱荷华州立大学从事博士后研究工作。2015年入职中国农科院植物保护研究所。中国农科院科技创新工程“抗病虫作物生态安全评价与利用创新团队”首席科学家；国家高层次人才特殊支持计划青年项目入选者；中国植物病理学会常务理事、副秘书长；中国作物学会分子育种分会委员；
中国生物工程学会生物农业分会委员；BMC Plant Biology和Frontiers in Genome Editing杂志副主编；Journal of Integrative Agriculture、aBIOTECH和生物技术通报编委。
研究组承担国家重点研发计划专项、国家农业重大科技项目、国家农业生物育种重大项目等多项。主要从事水稻抗性人工设计与基因编辑利用研究，涉及1）植物病原细菌基因编辑技术开发与合成生物学研究；2）水稻内源抗性基因人工定向进化与新种质挖掘；3）作物基因编辑技术开发与抗性基因人工设计。培育基因编辑抗病、耐除草剂水稻新材料和新品种，为实现我国农业绿色植保和可持续发展提供重要支撑。
目前已获得国家发明专利授权10项，在Cell Host & Microbe, Mol Plant, Nucleic Acids Res, Genome Biol, Plant Cell, Plant Biotech J, Plant Commun, Plant Physiol, Plant J, PLoS Pathog等国内外重要学术期刊上发表论文50多篇，其中7篇为ESI高被引论文。
联系方式：zhouhuanbin@caas.cn
个人网址：https://www.researchgate.net/profile/Huanbin_Zhou
代表性论文（#通讯作者）
1. X Li, S Zhang, C Wang, B Ren, F Yan, S Li, C Spetz, J Huang, X Zhou, H Zhou#. Efficient in situ epitope tagging of rice genes by nuclease-mediated prime editing. Plant Cell. 2024, koae316. doi: 10.1093/plcell/koae316.
2. M Yu, Y Kuang, C Wang, X Wu, S Li, D Zhang, W Sun, X Zhou, B Ren#, H Zhou#. Diverse nucleotide substitutions in rice base editing mediated by novel TadA variants. Plant Commun. 2024, 8:100926.
3. G Ma, F Yan, B Ren, Z Lu, H Xu, F Wu, S Li, D Wang, X Zhou & H Zhou#. Targeted gene evolution by LbCas12a nuclease-mediated tiling deletion in non-coding regions. Plant Commun. 2024, 5(4):100815.
4. M Wang, S Li, H Li, C Song, W Xie, S Zuo, X Zhou, C Zhou#, Z Ji# & H Zhou#. Genome editing of a dominant resistance gene for broad-spectrum resistance to bacterial diseases in rice without growth penalty. Plant Biotechnol.J. 2024, 22: 529-531.
5. X Wu, B Ren, L Liu, S Qiu, X Li, P Li, F Yan, H Lin, X Zhou, D Zhang# & H Zhou#. denine base editor incorporating the N-methylpurine DNA glycosylase MPGv3 enables efficient A-to-K base editing in rice. Plant Commun. 2023:100668.
6. F Yan, J Wang, S Zhang, Z Lu, S Li, Z Ji, C Song, G Chen, J Xu, J Feng, X Zhou & H Zhou#. CRISPR/FnCas12a-mediated efficient multiplex and iterative genome editing in bacterial plant pathogens without donor DNA templates. PLoS Pathog. 2023, 19(1): e1010961.
7. S Li#, C Wang, C You, X Zhou & H Zhou#.T-LOC: A comprehensive tool to localize and characterize the T-DNA integration sites.Plant Physiol. 2022, 190(3):1628-1639.
Commented by G Alex Mason. T-LOCked in: Identifying T-DNA insertions in plant genomes. Plant Physiol. 2022, 190(3):1547-1549.
8. S Li#, L Liu, W Sun, X Zhou & H Zhou#. A large-scale genome and transcriptome sequencing analysis reveals the mutation landscapes induced by high-activity adenine base editors in plants. Genome Biol. 2022, 23: 51.
9. K Wang*, H Zhou*& Q Qian#. The rice codebook: from reading to editing. Mol.Plant. 2022, 15: 569-572.
10. D Yan, B Ren, L Liu, F Yan, S Li, G Wang, W Sun, X Zhou & H Zhou#. High-efficiency and multiplex adenine base editing in plants using new TadA variants. Mol.Plant. 2021, 14(5): 722-731.（ESI高被引论文）
11. Z Xu, Y Kuang, B Ren, D Yan, F Yan, C Spetz, W Sun, G Wang, X Zhou# & H Zhou#. SpRY greatly expands the genome editing scope in rice with highly flexible PAM recognition. Genome Biol. 2021, 22: 6.
12. L Liu, Y Kuang, F Yan, S Li, B Ren, G Gosavi, C Spetz, X Li, X Wang, X Zhou & H Zhou#. Developing a novel artificial rice germplasm for dinitroaniline herbicide resistance by base editing of OsTubA2. Plant Biotech. J. 2021, 19(1): 5-7.
13. M Wang, Z Xu, G Gosavi, B Ren, Y Cao, Y Kuang, C Zhou, C Spetz, F Yan, X Zhou & H Zhou#. Targeted base editing in rice with CRISPR/ScCas9 system. Plant Biotech. J. 2020, 18(8): 1645-1647.
14. Y Kuang, S Li, B Ren, F Yan, C Spetz, X Li, X Zhou & H Zhou#. Base-editing-mediated artificial evolution of OsALS1 in planta to develop novel herbicide-tolerant rice germplasms. Mol.Plant. 2020, 13(4): 565-572. (ESI高被引论文)
15. B Ren, L Liu, S Li, Y Kuang, J Wang, D Zhang, X Zhou, H Lin# & H Zhou#.Cas9-NG greatly expands the targeting scope of the genome-editing toolkit by recognizing NG and other atypical PAMs in rice. Mol.Plant. 2019, 12(7): 1015-1026. （ESI高被引论文）
16. F Yan, Y Kuang, B Ren, J Wang, D Zhang, H Lin, B Yang, X Zhou & H Zhou#. Highly efficient A·T to G·C base editing by Cas9n-guided tRNA adenosine deaminase in rice.Mol.Plant. 2018, 11(4): 631-634. （ESI高被引论文）
17. B Ren, F Yan, Y Kuang, N Li, D Zhang, X Zhou, H Lin# & H Zhou#. Improved base editor for efficiently inducing genetic variations in rice with CRISPR/Cas9-guided hyperactive hAID mutant.Mol.Plant. 2018, 11(4): 623-626. （ESI高被引论文）
18. B Ren, F Yan, Y Kuang, N Li, D Zhang, H Lin# & H Zhou#. A CRISPR/Cas9 toolkit for efficient targeted base editing to induce genetic variations in rice.Sci. China. Life Sci. 2017, 60(5): 516-519. （第二届中国科协优秀科技论文遴选计划入选论文）
19. H Zhou, B Liu, DP Weeks, MH Spalding & B Yang. Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice.Nucleic Acids Res. 2014,42(17): 10903-10914. （ESI高被引论文）
20. H Zhou, J Lin, A Johnson, RL Morgan, W Zhong & W Ma. Pseudomonas syringae type III effector HopZ1 targets a host enzyme to suppress isoflavone biosynthesis and promote infection in soybean.Cell Host & Microbe. 2011,9(3): 177-186.
Commented by Andrew Bent. Pathogens Drop the Hint: Don't Forget Phytoalexin Pathways. Cell Host & Microbe. 2011, 9(3):169-70.
21. H Zhou, RL Morgan, DS Guttman & W Ma. Allelic variants of the Pseudomonas syringae type III effector HopZ1 are differentially recognized by plant resistance systems. Mol. Plant Microbe Interact. 2009,22(2): 176-189.
22. H Zhou, S Li, Z Deng, X Wang, T Chen, J Zhang, S Chen, H Ling, A Zhang, D Wang & X Zhang. Molecular analysis of three new receptor-like kinase genes from hexaploid wheat and evidence for their participation in the wheat hypersensitive response to stripe rust fungus infection. Plant J. 2007,52(3): 420-434.
