王如意，男，博士，副研究员，硕士生导师。

2011年获华中农业大学作物遗传育种硕士学位；2014-2016年在美国俄亥俄州立大学访问博士生；2017年获中国农业科学院植物病理学博士学位；2017-2019年任中国科学院植物研究所植物分子生理学重点实验室助理研究员；2019-2020年在美国俄亥俄州立大学访问博士后；2021年起任中国农业科学院植物保护研究所，植物病虫害综合治理全国重点实验室副研究员。

主要从事水稻抗稻瘟病信号通路关键蛋白质鉴定及功能研究。主持和参加国家自然科学基金青年项目、区域创新发展联合基金重点支持项目、国际（地区）合作与交流项目、国家重点研发青年科学家项目。研究结果发表论文40余篇，总引用1900余次，h-index 20。以第一/通讯作者在Science Advances、Genome Biology、Current Biology、Nucleic Acids Research和Molecular Plant等杂志发表论文18篇。博士论文入选“2017年度中国农业科学院优秀博士学位论文”，研究论文被Current Biology专题评论，Faculty Opinions推荐，研究成果获“2022年中国农业科学院科学技术成果青年科技创新奖”，“2024年北京植物病理学会优秀科技论文一等奖”，入选“北京市科学技术协会第十七届青年优秀科技论文”，担任aBIOTECH期刊青年编委, Plant Cell & Environment和Molecular Plant Pathology等杂志审稿人。

研究方向：（1）水稻NLR类型抗病蛋白介导的抗稻瘟病分子机制；（2）蛋白质翻译后修饰调控稻瘟菌和水稻互作机理；（3）水稻抗稻瘟病关键蛋白质的挖掘和功能解析。

E-mail：wangruyi@caas.cn

 代表性论文

1.    Zhang C., Fang L., He, F., You, X., Wang, M., Zhao, T., Hou Y, Xiao N, Li A, Yang J, Ruan J, Francis F, Wang G.-L., Wang R^*., Ning Y^*. (2025). Ubiquitination of OsCSN5 by OsPUB45 activates immunity by modulating the OsCUL3a-OsNPR1 module. Science Advances 11(1): eadr2441. (IF:11.7)

2.    Hao Z., Xu X., Wang GL., Wang R.*, Ning Y.*. (2025). E3 ubiquitin ligases at the frontline of antiviral defence. Nature Plants, https://doi.org/10.1038/s41477-025-02008-7 (IF:15.8)

3.    Tao H., Ning Y., He F.^*, Wang R^*. (2025) Attenuation of plant immune kinases by U-box type E3 ubiquitin ligases. Science China Life Sciences. https://doi.org/10.1007/s11427-025-2903-2 (IF:8.0)

4.    Zhang F., Wang M., Wang G.-L., Ning Y^*., Wang R.^* (2023). Insights into Metabolite Biosynthesis and Regulation in Rice Immune Signaling. Trends in Microbiology 31(3).225-228 (IF:14.0)

5.    Wang R., Wang G-L. and Ning Y. (2023). Harnessing nanobodies to expand the recognition spectrum of plant NLRs for diverse pathogens. aBIOTECH, 4:272-276.（IF:4.6） 

6.    Wang R., Xu X., Wang G.-L. and Ning Y. (2022). Ubiquitination of susceptibility proteins modulates rice broad-spectrum resistance. Trends in Plant Science, 27 (4), 322-324. (IF:20.5)

7.    Wang R., You X., Zhang C., Fang H., Wang M., Zhang F., Kang H., Xu X., Liu Z., Wang J., Zhao Q., Wang X., Hao Z., He F., Tao H., Wang D., Wang J., Fang L., Qin M., Zhao T., Zhang P., Xing H., Xiao Y., Liu W., Xie Q., Wang G.-L. and Ning Y. (2022). An ORFeome of rice E3 ubiquitin ligases for global analysis of the ubiquitination interactome. Genome Biology 23, 154. (IF:12.3)

8.    Wang J.^#, Wang R.^#, Fang H., Zhang C., Zhang F., Hao Z., You X., Shi X., Park C.H., Hua K., He F., Bellizzi M., Xuan Vo K.T., Jeon J.-S., Ning Y., Wang G.-L. (2021). Two VOZ Transcription Factors Link An E3 Ligase and An NLR Immune Receptor to Modulate Immunity in Rice. Molecular Plant 14 (2), 253–266. (IF:21.9, Cited by 79)

9.    Tian W.^#, Wang R.^#, Bo C., Yu Y., Zhang Y., Shin G.-I., Kim W.-Y., and Wang L. (2021). SDC mediated DNA methylation-controlled clock pace by interacting with ZTL in Arabidopsis. Nucleic Acids Research 49 (7), 3764-3780. (IF:19.2)

10. Wang R., He F., Ning Y., Wang G.-L. (2020). Fine-Tuning of RBOH-Mediated ROS Signaling in Plant Immunity. Trends in Plant Science 25 (11), 1060-1062.  (IF:18.3) 

11. Wang R., Wang G-L. and Ning Y. (2019). PALs: Emerging Key Players in Broad-Spectrum Disease Resistance. Trends in Plant Science, 24, 785-787. (IF: 14.4)

12. Wang R., Ning Y., Shi X., He F., Zhang C., Fan J., Jiang N., Zhang Y., Zhang T., Hu Y., Bellizzi M. and Wang G.-L* (2016). Immunity to Rice Blast Disease by Suppression of Effector-Triggered Necrosis. Current Biology 26, 2399–2411. (IF: 8.851). Referred to by Zhou J. (2016). Plant Pathology: A Life and Death Struggle in Rice Blast Disease Current Biology 26, R843-R845)

13.  Wang, R., Ji, Z., Kou, Y., Yang, X., Huang, W., Sun, Z., Zuo, S., Li, Z., Xiong, Y., Deng, Y., Zhou, X., Wang, G. L., Liu, J., & Ning, Y. (2025). Occurrence and integrated control of major rice diseases in China. New Plant Prot e70004. https://doi.org/10.1002/npp2.70004

14. Ning Y.^#, Wang R.^#, Shi X., Zhou X., and Wang G-L. (2016). A Layered Defense Strategy Mediated by Rice E3 Ubiquitin Ligases against Diverse Pathogens. Molecular Plant ,9, 1096–1098. (IF: 8.8)

15.  You X.^#, Fang H.^#, Wang R.^#, Wang G-L. and Ning Y. (2020). Phenylalanine Ammonia Lyases Mediate Broad-Spectrum Resistance to Pathogens and Insect Pests in Plants, Science Bulletin, 65, 1425-1427. (IF:11.8)

16.  Ning Y.^#, Shi X.^#, Wang R.^#, Fan J., Park C.H., Zhang C., Zhang T., Ouyang X., Li S. and Wang G-L. (2015). OsELF3-2, an Ortholog of Arabidopsis ELF3, Interacts with the E3 Ligase APIP6 and Negatively Regulates Immunity against Magnaporthe oryzae in Rice, Molecular Plant, 8, 1679-1682. (IF:7.1)

17.  Qin M., Tao H., Shi X., Zhang C., He F., Wang M., Liu Z., Wang J., Zhang R., Wang S., Wang G-L., Ning Y., Wang R. (2023) Transcriptome Analysis of oserf922 Mutants Reveals New Insights into Rice Blast Resistance, Rice Science, 30 (5), 374-378. (IF:4.8)

18.  王如意, 刘 杰, 冯 琴, 张熠玚，肖宁，吴俊，郑文静，李爱宏，宁约瑟 （2023）稻瘟病抗性分子机制及抗病育种策略研究进展. 植物保护，49（5）7-19