中文名：宋福平EDUCATION
1998.09～2001.07 Ph. D. in Crop Genetics & Breeding Northeast Agricultural University, Harbin, China
1995.09～1998.07 M. Sc. in Entomology Northeast Agricultural University, Harbin, China
1987.09～1991.07 B.S. in Zoology Fudan University, ShangHai, China
RESEARCH EXPERIENCE
2010-Present Professor, Institute of Plant Protection, CAAS, China
2003-2009 Associate Professor, Institute of Plant Protection, CAAS, China
2007-2008 Post-doc Associate, Génétique Microbienne et environnement, INRA, France
2001-2003 Post-doc Associate, Biotechnology Research Institute, CAAS, Beijing. China.
1991-2001 Assistant Professor, Northeast Agricultural University, Harbin. China.
Research Area：
The main aim of my works is how to increase the Cry protein production and the persistance of B. thuringiensis biocontrol agents. Thus, my interests include: 1. Mechanism of spore formation 2. Mechanism of crystal formation 3. Regulation of different types of toxin genes 4. Regulation of metabolism pathways related to Cry protein production
Publications：
1. Deng Chao, Slamti L, Raymond Ben, Liu Guiming, Lemy C, Gominet M, Yang Jingni, Wang Hengliang, Peng Qi, Zhang Jie, Lereclus Didier*, Song Fuping*. 2015. Division of labour and terminal differentiation in a novel Bacillus thuringiensis strain. International Society for Microbial Ecology Journal. 9: 286-296.
2. Yang Bi, Yanrui Zhang, Changlong Shu, Neil Crickmore, Qinglei Wang, Lixin Du, Fuping Song, Jie Zhang*. 2015. Genomic sequencing identifies novel Bacillus thuringiensis Vip1/Vip2 binary and Cry8 toxins that have high toxicity to Scarabaeoidea larvae. Applied Microbiology and Biotechnology. 99(2):753-760.
3. Qi Peng, Min Yang, Wei Wang, Lili Han, Guannan Wang, Pengyue Wang, Jie Zhang, Fuping Song*. 2014. Activation of gab cluster transcription in Bacillus thuringiensis byγ-aminobutyric acid or succinic semialdehyde is mediated by the Sigma 54-dependent transcriptional activator GabR. BMC Microbiology. 14: 306-317.
4. Lili Geng, Xiaohong Duan, Chun Liang, Changlong Shu, Fuping Song, Jie Zhang*. 2014. Mining tissue-specific contigs from peanut (Arachis hypogaea L.) for promoter cloning by deep transcriptome sequencing. Plant Cell Physiology. 55(10): 1793-1801.
5. Ying Li, Changlong Shu, Xuewen Zhang, Neil Crickmore, Gemei Liang, Xingfu Jiang, Rongmei Liu, Fuping Song, Jie Zhang*. 2014. Mining rare and ubiquitous toxin genes from a large collection of Bacillus thuringiensis strains. Journal of Invertebrate Pathology. 122: 6-9.
6. Changmei Zhou, Qingyun Zheng, Qi Peng, Lixin Du, Changlong Shu, Jie Zhang, Fuping Song*. 2014. Screening of cry-type promoters with strong activity and application in Cry protein encapsulation in a sigK mutant. Applied Microbiology and Biotechnology. 98: 7901-7909.
7. Zhe Zhang, Min Yang, Qi Peng, Guannan Wang, Qingyun Zheng, Jie Zhang, Fuping Song*. 2014. Transcription of the lysine-2, 3-aminomutase gene in the kam locus of Bacillus thuringiensis subsp. kurstaki HD73 Is controlled by both δ54 and δK factors. Journal of Bacteriology. 196(16): 2934-2943.
8. Chao Deng, Qi Peng, Fuping Song,* Didier Lereclus*. 2014. Regulation of cry gene expression in Bacillus thuringiensis. Toxins. R6: 2194-2209. (Review)
9. Zishan Zhou, Huiyan Lin, Ying Li, Changlong Shu, Fuping Song, Jie Zhang*. 2014. The minimal active fragment of the Cry1Ai toxin is located between 36I and 605I. Journal of Integrative Agriculture, 13(5): 1036-1042.
10. Yueming Shan, Changlong Shu, Neil Crickmore, Chunqin Liu, Wensheng Xiang, Fuping Song, Jie Zhang*. 2014. Cultivable Gut Bacteria of Scarabs (Coleoptera: Scarabaeidae) inhibit Bacillus thuringiensis multiplication. Environmental Entomology. 43(3): 612-616.
11. Yanhua Jia, Can Zhao, Qinglei Wang, Changlong Shu, Xiaojie Feng, Fuping Song, Jie Zhang*. 2014. A genetically modified broad-spectrum strain of Bacillus thuringiensis toxic against Holotrichia parallela, Anomala corpulenta and Holotrichia oblita. World Journal of Microbiology & Biotechnology. 30(2): 595-603.
12. Changlong Shu, Dongming Liu, Zishan Zhou, Jilin Cai, Qi Peng, Jiguo Gao, Fuping Song, Jie Zhang*. 2013. An improved PCR-RFLP method for the identification of cry1-type genes. Applied and Environmental Microbiology. 9(21): 6706-6711.
13. Changlong Shu, Huiqin Su, Jie Zhang, Kanglai He, Dafang Huang, Fuping Song*. 2013. Characterization of cry9Da4, cry9Eb2, and cry9Ee1 genes from Bacillus thuringiensis strain T03B001. Applied Microbiology and Biotechnology. 97(22): 9705-9713.
14. Changlong Shu, Jingtao Zhang, Guihua Chen, Gemei Liang, Kanglai He, Neil Crickmore, Dafang Huang, Jie Zhang*, Fuping Song*. 2013. Use of a pooled clone method to isolate a novel Bacillus thuringiensis Cry2A toxin with activity against Ostrinia furnacalis. Journal of Invertebrate Pathology. 114: 31-33.
15. Lili Geng, Jing Chi, Changlong Shu, Peter Gresshoff, Fuping Song, Dafang Huang, Jie Zhang*. 2013. A chimeric cry8Ea1 gene flanked by MARs efficiently controls Holotrichia parallela. Plant Cell Reprts. 32: 1211-1218.
16. Weiyu Jiang, Lili Geng, Pingli Dai, Zhihong Lang, Changlong Shu, Yi Lin, Ting, Zhou, Fuping Song, Jie Zhang*. 2013. The Influence of Bt-transgenic maize pollen on the bacterial diversity in the midgut of Chinese honeybees, Apis cerana cerana. Journal of Integrative Agriculture. 12(3): 474-482.
17. Jingni Yang, Qi Peng, Zhen Chen, Chao Deng, Changlong Shu, Jie Zhang*, Dafang Huang, Fuping Song*. 2013. Transcriptional regulation and characteristics of a novel N- acetylmuramoyl - L-alanine amidase gene involved in Bacillus thuringiensis mother cell lysis. Journal of Bacteriology. 195 (12): 2887-2897.
18. Guiming Liu, Lai Song, Changlong Shu, Pinshu Wang, Chao Deng, Qi Peng, Didier Lereclus, Xumin Wang, Dafang Huang, Jie Zhang*, Fuping Song*. 2013. Complete genome sequence of Bacillus thuringiensis subsp. kurstaki strain HD73. Genome Announcements. Vol.1 (2) e00080-13.
19. Lili Geng, Hongjuan Cui, Pingli Dai, Zhihong Lang, Changlong Shu, Ting Zhou, Fuping Song, Jie Zhang*. 2013. The influence of Bt-transgenic maize pollen on the bacterial diversity in the midgut of Apis mellifera ligustica. Apidologie. 44: 198-208.
20. Lixin Du, Lili Qiu, Qi Peng, Didier Lereclus, Jie Zhang, Fuping Song*, Dafang Huang*. 2012. Identification of the promoter in the intergenic region between orf1 and cry8Ea1 controlled by Sigma H factor. Applied and Environmental Microbiology. 78: 4164-4168.
21. Hui Yang, Pinshu Wang, Qi Peng, Rong Rong, Chunxia Liu, Didier Lereclus, Jie Zhang, Fuping Song*, Dafang Huang*. 2012. Weak transcription of the cry1Ac gene in nonsporulating Bacillus thuringiensis cells. Applied and Environmental Microbiology. 78: 6466-6474.
22. Lili Geng, Lihong Niu, Peter M. Gresshoff, Changlong Shu, Fuping Song, Dafang Huang, Jie Zhang*. 2012. Efficient production of Agrobacterium rhizogenes-transformed roots and composite plants in peanut (Arachis hypogaea L.). Plant Cell Tiss Organ Cult. 109: 491-500.
23. Fuping Song*, Qi Peng, Julien Brillard, Christophe Buisson, Mark de Been, Tjakko Abee, Véronique Broussolle, Dafang Huang, Jie Zhang, Didier Lereclus, Christina Nielsen - LeRoux*. 2012. A multicomponent sugar phosphate sensor system specifically induced in Bacillus cereus during infection of the insect gut. The FASEB Journal. 26: 3336-3353.
24. Jing Xue, Zishan Zhou, Fuping Song, Changlong Shu, Dafang Huang, Jie Zhang*. 2011. Identification of the minimal active fragment of the Cry1Ah toxin. Biotechnol Letter. 33: 531–537.
25. Lili Geng, Lihong Niu, Changlong Shu, Fuping Song, Dafang Huang, Jie Zhang*. 2011. High-efficiency regeneration of peanut (Arachis hypogaea L.) plants from leaf discs. African Journal of Biotechnology. 10(59), 12680-12682.
26. Shuyuan Guo, Jie Li, Yanfeng Liu, Fuping Song, Jie Zhang*. 2011. The role of DNA binding with the Cry8Ea1 toxin of Bacillus thuringiensis. FEMS Microbiol Letter. 317: 203-210.
27. Shuyuan Guo*, Chunlu Zhang, Xiaoyin Lin , Yanrui Zhang , Kanglai He, Fuping Song, Jie Zhang*. 2011. Purification of an active fragment of Cry1Ie toxin from Bacillus thuringiensis. Protein Expression and Purification. 78: 204-208.
28. Li Zhu, Qi Peng, Fuping Song*, Yanan Jiang, Changpo Sun, Jie Zhang, Dafang Huang*. 2010. The structure and regulation of the gab gene cluster involved in the GABA shunt controlled by a σ54 factor in Bacillus thuringiensis. Journal of Bacteriology. 192(1): 346-355.
29. Hui Yang, Fuping Song*, Jie Zhang, Dafang Huang. 2010. In vivo fluorescence observation of parasporal inclusion formation in Bacillus thuringiensis. Science in China. 53(9): 1106-1111.
30. Jingjing Liu, Guixin Yan, Changlong Shu, Can Zhao, Cunqin Liu, Fuping Song, Lin Zhou, Junlan Ma, Jie Zhang, Dafang Huang. 2010. Construction of a Bacillus thuringiensis engineered strain with high toxicity and broad pesticidal spectrum against coleopteran insects. Applied Microbiology and Biotechnology. 87(1): 243-249.
31. Changlong Shu, Guixin Yan, Rongyan Wang, Jie Zhang, Dafang Huang, Fuping Song*. 2009. Characterization of a novel cry8 gene specific to Melolonthidae pests: Holotrichia oblita. Applied Microbiology and Biotechnology. 84: 701-707.
32. Shuyuan Guo, Sheng Ye, Yanfeng Liu, Jing Xue, Fuping Song, Jie Zhang, Dafang Huang, Zihe Rao. 2009. Crystal structure of Bt Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela.. Journal of Structural Biology. 168: 259-266.
33. Changlong Shu, Hong Yu, Rongyan Wang, Shuliang Fen, Xudong Su, Dafang Huang, Jie Zhang, Fuping Song*. 2008. Characterization of two novel cry8 genes from Bacillus thuringiensis Strain BT185. Current Microbiology. 58: 389-392.
34. Jing Xue, Gemei Liang, Neil Crickmore, Haitao Li, Kanglai He, Fuping Song, Xue Feng, Dafang Huang, Jie Zhang. 2008. Cloning and characterization of a novel Cry1A toxin from Bacillus thuringiensis with high toxicity to the Asian corn borer and other lepidopteran insects. FEMS Microbiology Letters. 280: 95-101.
35. Tiemei Shao, Linquan Bai, Jie Zhang, Guangjun Wang, Liu D., Zhuofu Li, Jianmi Liu, Fuping Song, Dafang Huang. 2008. A Nonribosomal Peptide Synthetase Gene tzw1 is Involved in Zwittermicin A Biosynthesis in Bacillus thuringiensis G03. Current Microbiology. 57: 61-65.
36. XuDong Su, ChangLong Shu, Jie Zhang, DaFang Huang, JianXin Tan, FuPing Song*. 2007. Identification and Distribution of Bacillus thuringiensis Isolates from Primeval Forests in Yunnan and Hainan Provinces and Northeast Region of China. Agricultural Sciences in China. 6(11): 1345-1351.
37. Jinhuan Liu, Jie Zhang, DafangHuang, Fuping Song*. 2007. Identification of vip3A-type genes from Bacillus thuringiensis strains and characterization of a novel vip3A-type gene. Letters in Applied Microbiology. 45: 432-438.
38. Changlong Shu, Jie Zhang, Dafang Huang, Fuping Song*. 2007. Improving toxicity of Bacillus thuringiensis strain contains the cry8Ca gene specific to Anomala corpulenta larvae. Current Microbiology. 55: 492-496.
39. Dafang Huang, Jie Zhang, Fuping Song, Zhihong Lang. 2007. Microbial Control and Biotechnology Research on Bacillus thuringiensis (Bt) in China. Journal of Invertebrate Pathology. 95(3): 175-180.
40. Hong Yu, Jie Zhang, Dafang Huang, Jiguo Gao, Fuping Song*. 2006. Characterization of Bacillus thuringiensis strain Bt185 toxic to the Asian cockchafer: Holotrichia parallela. Current Microbiology. 53:13-17.
41. Guangjun Wang，Jie Zhang, Fuping Song, Dafang Huang et al. 2006. Engineered Bacillus thuringiensis G033A with Broad Insecticidal Activity against Lepidopteran and Coleopteran Pests. Applied Microbiology and Biotechnology. 72: 924-930.
42. Tianpei Huang，Jingjing Liu，Fuping Song，Jie Zhang. 2004. Identification, distribution pattern of IS231 elements in Bacillus thuringiensis and their phylogenetic analysis. FEMS Microbiology Letters. 241: 27-32.
43. Fuping Song, Jie Zhang, Dafang Huang* et al. 2003. Identification of cry1I-type genes from Bacillus thuringiensis strains and charaterization of a novel cry1I-type gene. Applied and Environmental Microbiology. 69(9): 5207-5211.
