中文名：邱德文EDUCATION
1977-1981: B.S., Department of Plant Protection, Hunan Agricultural University, China.
1983-1987: M.S., Department of Plant Pathology, Beijing Agricultural University, China.
1993-1997: Ph.D., Department of Plant Pathology, Beijing Agricultural University, China.
WORKING EXPERIENCE
Dec., 1981-Aug., 1983: Assistant, Institute of Vegetable, Changsha, China.
Jan., 1986-Dec., 1989: Associate professor, Department of Plant Protection, Institute of Rice, Hangzhou, China
Dec., 1989-Sept., 1995: Associate professor, Institute of Organic Chemistry, Nankai University
Sept., 1995-Jan., 1997: Visiting scientist, Department of Plant Pathology, Life Academy of Sciences, Cornell University, New York, USA.
Jan. 1997-Nov., 2002: Scientist, Eden Biological Corporation, Seattle, USA
Nov., 2002-now: Deputy director of Institute of Plant Protection, CAAS
Research Area：
I have been mainly working on biopesticide engineering including interrelationship between microbial protein and plant, biological protein detection and function study. I extensively study the molecular mechanism of protein elicitor induced systematic acquired resistance and growth promotion. In addition, I also work on microbial protein pesticide formulation and application technology for protein pesticide. Up to now we have isolated a microbial protein, which can activate plant resistance and enhance crop yield. We have purified the protein, obtained the amino-acid sequences and studied the protein construct. 3% wettable plant activate protein pesticide is registered for commercializatiom in Ministry of Agriculture in China (LS-20091262). It was honored to the Presidential Award of Green Chemistry Challenge by Environmental Protection Agency of United State in 2001. Patients on microbial protein pesticide were filed and approved in U.S.A. and/or China.
Publications：
1. Mahesh Kulye*, Hua Liu, Yuliang Zhang, Hongmei Zeng, Xiufen Yang, Dewen Qiu*. 2012. Hrip1, a novel protein elicitor from necrotrophic fungus, Alternaria tenuissima, elicits cell death, expression of defence-related genes and systemic acquired resistance in tobacco. Plant, Cell and Environment, 35: 2104-2120
2. Bingnan Wang, Xiufen Yang*, Hongmei Zeng, Hua Liu, Tingting Zhou, Beibei Tan, Jingjing Yuan, Lihua Guo, Dewen Qiu*. 2012. The purification and characterization of a novel hypersensitive-like response-inducing elicitor from Verticillium dahliae that induces resistance responses in tobacco. Appl Microbiol Biotechnol, 93:191-201
3. Haoqian Wang, Xiufen Yang, Lihua Guo, Hongmei Zeng, Dewen Qiu*.2015. PeBL1, a novel Protein elicitor from Brevibacillus laterosporus Strain A60, activates defense responses and systemic resistance in Nicotiana benthamiana. Applied and Environmental Microbiology, 81(8):2706-2716
4. Wenxian Wu, Zhiwei Cheng, Mengjie Liu, Xiufen Yang, Dewen Qiu*. 2014. C3HC4-Type RING Finger Protein NbZFP1 Is Involved in Growth and Fruit Development in Nicotiana benthamiana. PLoS ONE 9(6): e99352. doi:10.1371/journal.pone.0099352
5. Jianjun Mao, Quan Liu, Xiufen Yang, Chengzu Long, Mingzhi Zhao, Hongmei Zeng, Jingjing Yuan, Dewen Qiu *. 2010. Purification and expression of a protein elicitor from Alternaria tenuissima and elicitor-mediated defense responses in tobacco. Annals of Applied Biology, 156: 411-420
6. Guangyue Li，Xiufen Yang，Hongmei Zeng , Jianjun Mao, Hua Liu, Dewen Qiu*. 2010. Stable isotope labeled mass spectrometry for the quantification of protein expression induced by PeaT1, Science China (Life Science), 53(12):1410-1417
7. Dewen Qiu*, Jianjun Mao, Xiufen Yang, Hongmei Zeng. 2009. Expression of an elicitor-encoding gene from Magnaporthe grisea enhances resistance against blast disease in transgenic rice. Plant Cell Reports, 28(6): 925-933
8. Mahesh S Kulye, Hua Liu, Dewen Qiu*. 2012. The role of radical burst in plant defense responses to necrotrophic fungi. Journal of Integrative Agriculture 11(7): 116-121
9. Lei Han, Zheng Liu, Xinqi Liu, Dewen Qiu*. 2012. Purification, crystallization and preliminary X-ray diffraction analysis of the effector protein PevD1 from Verticillium dahliae. Acta Crystallographica Section F 68: 802-805
10. Mengjie Liu, Xinqi Liu, Hongmei Zeng and Dewen Qiu*. 2013. Purification, crystallization and preliminary X-ray diffraction analysis of effector protein MoHrip2 from Magnaporthe oryzae. Acta Crystallographica Section F69, 463-467
11. Wenxian Liu, Hongmei Zeng∗, Zhipeng Liu, Xiufen Yang, Lihua Guo, Dewen Qiu*. 2014. Mutational analysis of the Verticillium dahliae protein elicitor PevD1 identifies distinctive regions responsible for hypersensitive response and systemic acquired resistance in tobacco. Microbiological Research 169 : 476-482
12. Yunhua Zhang, Xiufen Yang*, Hongmei Zeng, Lihua Guo, Jingjing Yuan, Dewen Qiu*. 2014. Fungal elicitor protein PebC1 from Botrytis cinerea improves disease resistance in Arabidopsis thaliana. Biotechnol Lett 36:1069-1078
13. Jing Zhao, Lihua Guo*, Hongmei Zeng, Xiufen Yang, Jingjing Yuan, Huaixing Shi, Yehui Xiong, Mingjia Chen, Lei Han, Dewen Qiu*. 2012. Purification and characterization of a novel antimicrobial peptide from Brevibacillus laterosporus strain A60. Peptides 33: 206-211
14. Jun Yang, Hongmei Zeng*, Huafeng Lin, Xiufen Yang, Zheng Liu, Lihua Guo, Jingjing Yuan, Dewen Qiu*.2012. An insecticidal protein from Xenorhabdus budapestensis that results in prophenoloxidase activation in the wax moth. Journal of Invertebrate Pathology, 110 (2012) 60-67
15. Huaixing Shi, Hongmei Zeng*, Xiufen Yang, Jing Zhao, Mingjia Chen, Dewen Qiu* 2012. An insecticidal protein from Xenorhabdus ehlersii triggers prophenoloxidase activation and hemocyte decrease in Galleria mellonella. Current Microbiology 64: 604-610
16. Mingjia Chen, Hongmei Zeng*, Dewen Qiu, Lihua Guo, Xiufen Yang, Huaixing Shi, Tingting Zhou, Jing Zhao. 2012. Purification and characterization of a novel hypersensitive response-inducing elicitor from Magnaporthe oryzae that triggers defense response in rice. PLoS ONE 7(5): e37654
17. Yao Xiao, Fanlu Meng, Dewen Qiu, Xiufen Yang*. 2012. Two novel antimicrobial peptides purified from the symbiotic bacteria Xenorhabdus budapestensis NMC-10. Peptides, 35, 253-260
18. Donghai Peng, Dewen Qiu, Lifang Ruan, Chenfei Zhou, Ming Sun*. 2011. Protein Elicitor PemG1 from Magnaporthe grisea Induces Systemic Acquired Resistance (SAR) in Plants .MPMI 24(10):1239-1246
19. Tinging Zhou, Hongmei Zeng*, Dewen Qiu, Xiufen Yang, Bingnan Wang, Mingjia Chen, Lihua Guo, Shuangchao Wang. 2011. Global transcriptional responses of Bacillus subtilis to xenocoumacin 1. Journal of Applied Microbiology 111: 652-662
20. Yi Zhang, Yunhua Zhang, Dewen Qiu, Hongmei Zeng, Lihua Guo, Xiufen Yang*. 2015. BcGs1, a glycoprotein from Botrytis cinerea, elicits defence response and improves disease resistance in host plants. Biochemical and Biophysical Research Communications. 457:627-634
21. Bingwu Bu, Dewen Qiu, Hongmei Zeng, Lihua Guo, Jingjing Yuan, Xiufen Yang*. 2014. A fungal protein elicitor PevD1 induces Verticillium wilt resistance in cotton. Plant Cell Reports, 14: 461-470
22. Xuecong Peng，Dewen Qiu，Hongmei Zeng，Lihua Guo，Xiufen Yang*，Zheng Liu*.2015. Inducible and constitutive expression of an elicitor 1 gene Hrip1 from Alternaria tenuissima enhances stress tolerance in Arabidopsis. Transgenic research, 24:135-145
23. Wei Zhang, Xiufen Yang*, Dewen Qiu, Lihua Guo, Hongmei Zeng, 2011. Jianjun Mao, Qiufeng Gao. PeaT1-induced systemic acquired resistance in tobacco follows salicylic acid-dependent pathway, Molecular biological report, 38（4）：2549-56
24. Hua Liu, Hongmei Zeng*, Qing Yao, Jingjing Yuan, Yuliang Zhang, Dewen Qiu, Xiufen Yang, Huaiwen Yang, Zheng Liu. 2012. Steine rnema glaseri surface enolase: molecular cloning, biological characterization and role in host immune suppression. Molecular and Biochemical Parasitology, 89- 98
